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What is osteogenesis imperfecta (brittle bone disease)?

Osteogenesis imperfecta, commonly known as brittle bone disease, is a lifelong genetic condition affecting the body’s ability to make collagen protein, causing fragile and brittle bones. Without the right amount of collagen, bones are weak and highly susceptible to trauma, causing frequent fractures and breaks. Common symptoms of the condition are frequent broken bones, gradual bending of the leg and arm bones, short stature, weak muscles, and, in time, loss of the ability to walk.

What issues do children with brittle bones face?



Weakened bones can lead to abnormal bending, painful breaks, and fractures



Children with frequent broken bones are vulnerable to bullying and exclusion



Children can lose the ability to walk, preventing them from attending school

How does surgery change a child’s life?

  • The condition can be managed, though not cured, through intravenous medicine to strengthen the bones (bisphosphonates) and surgery to straighten the bones.
  • Children experience restored confidence and hope as they are accepted into community life.
  • Mobility improves so children can run, play, walk pain-free, completing school which lead to more opportunities.

Miracles happen every day at Tebow CURE


Prince has a genetic condition that causes his bones to break often. His parents struggled to afford treatment for Prince’s frequent broken bones. Now at TEBOW Cure, they can receive the medical care Prince needs at no cost to them.

Contact Us

Tebow CURE’s mission is to provide every child living with a disability the physical, emotional, and spiritual care they need to heal. If you have questions about becoming a patient or a partner with CURE, please contact us.

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